tailored approaches for different pathological scenarios
a new system for ototoxicity-preventing compounds screening
to evaluate effects and brain penetrance of drugs and agents
our commitment on fostering research and innovation
Multiparametric functional assays for Mode of Action understanding and cell products for discovery applications.
Cell-based models to recreate in vitro pathological tissues complexity for more efficient drug discovery.
A collection of tailored assays for early detection of mithocondrial deficiencies and toxicity.
An innovative approach to study ion channels activity and cell signaling.
OTOTOX is designed to screen compounds preventing ototoxicity and to investigate their mechanism of action with a fast and high-throughput approach.
The platform can also be employed to exclude ototoxic side-effects of candidate drugs.
Our in vitro human BBB model is composed of an upper layer of human vascular endothelial cells (HMVEC) and a lower layer of human astrocytes (NHA), separated by a permeable support.
This BBB Model can be used to test the brain penetrance of candidate drugs and to evaluate the effect of BBB protective/disruptive agents.
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